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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC6
All Species:
11.82
Human Site:
S24
Identified Species:
21.67
UniProt:
Q03468
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03468
NP_000115.1
1493
168416
S24
C
L
Q
S
Q
P
V
S
N
N
E
E
M
A
I
Chimpanzee
Pan troglodytes
XP_507781
1491
168031
S24
C
L
Q
S
Q
P
V
S
N
N
E
E
M
A
I
Rhesus Macaque
Macaca mulatta
XP_001107536
1496
168876
S24
Y
L
Q
S
Q
P
V
S
N
N
E
E
M
A
I
Dog
Lupus familis
XP_534944
1486
168108
S29
T
E
Q
S
Q
C
V
S
D
K
Q
E
M
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
NP_001100766
1325
148468
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508174
968
109820
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24368
1027
118855
Honey Bee
Apis mellifera
XP_001120586
932
107557
Nematode Worm
Caenorhab. elegans
P41877
1009
116656
Sea Urchin
Strong. purpuratus
XP_001193315
953
107227
Poplar Tree
Populus trichocarpa
XP_002307656
1206
134941
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWY3
1057
122611
Baker's Yeast
Sacchar. cerevisiae
P40352
1085
124509
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.2
83.3
N.A.
N.A.
70.1
N.A.
44.6
N.A.
N.A.
N.A.
N.A.
20
31.4
20.6
36.4
Protein Similarity:
100
99.4
97.9
89.1
N.A.
N.A.
76.4
N.A.
52.2
N.A.
N.A.
N.A.
N.A.
35.7
43.8
35.7
45.8
P-Site Identity:
100
100
93.3
53.3
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
0
0
0
P-Site Similarity:
100
100
93.3
66.6
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
0
0
0
Percent
Protein Identity:
29.4
N.A.
N.A.
23.5
28.4
N.A.
Protein Similarity:
44.9
N.A.
N.A.
38.2
43.9
N.A.
P-Site Identity:
0
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
0
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
0
% A
% Cys:
16
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
24
31
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
31
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
31
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
24
24
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
31
0
31
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
31
0
0
0
31
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
31
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _